Russia's Ministry for Emergency Situations says 50 people have been killed in a crash at the airport in Kazan, the capital of Russia's Tatarstan region, RFE/RL informs.
Emergency Situations Ministry spokeswoman Irina Rossius said the Boeing 737 plane broke up as it was landing.
The plane had departed Moscow's Domodedyevo Airport earlier on November 17 with 44 passengers and six crew members aboard.
Reports said the plane was making a second attempt at landing when it hit the ground and burst into flames. Firefighters rushed to the scene and put the flames out.
Officials were cautioning against speculating about the cause of the crash until the plane's black box is found.
President Vladimir Putin ordered the government to set up a commission for an urgent investigation of the accident.
As reported, one of those killed in the plane crash was Irek Minnikhanov, the son of the republic's president, Rustam Minnikhanov, and Aleksandr Antonov, the head of the Federal Security Service department in Tatarstan.